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- Samaritans
- Sands
- SARCS(Sexual Assualt Response Co-ordination Service)
- School clothing & footwear grant
- Scotland Domestic Abuse and Forced Marriage Helpline
- Scottish Association for Mental Health (SAMH)
- Scottish Autism
- Scottish Borders Housing Association
- Scottish Borders Rape Crisis
- Scottish Child Payment
- Scottish Childminding Association
- Scottish Families Affected by Drugs and Alcohol
- Scottish Refugee Council
- Scottish Welfare Fund
- Scottish Womens Rights Centre
- See Me
- Selkirk Foodbank
- Selkirk Pantry-Philiphaugh Community Centre
- Shakti Womens Aid
- Shelter Scotland
- SHOUT
- SiMBA
- Six Ways to be Well
- Skills Development Scotland(SDS)
- Skills Development Scotland-All age service
- Social Work-Support kinship/foster and adoption placements
- Solihull Approach-Parenting
- Stable Life
- Statutory Maternity Pay (SMP)
- Statutory Parental Bereavement Leave and Pay
- Statutory paternity pay (SPP) for fathers/partners
- Statutory Shared Parental Pay
- Stay Alive App
- Support for Self Harm-SHNS
- Surviving Economic Abuse
- Sustainable Borders